Symptoms of Ischemia

Patients experience ischemia in different ways. Classic anginal symptoms include pain or discomfort in the chest or adjacent areas (arm, shoulder, back, neck, or jaw) brought on by physical exertion or emotional stress.1,2 Stable angina is relieved within minutes by rest or nitroglycerin.2

Anginal equivalents, such as those listed below, are symptoms of myocardial ischemia other than pain or angina.2 The following quotations from real patients illustrate how patients describe angina and anginal equivalents3:

Dyspnea on exertion

"I am short of breath and need to gasp for air."

Faintness

"Angina is like a lightning shock."

Fatigue

"I feel like a truck is parked on my chest."

Indigestion

"I feel like I am going to explode."


References

  • American Heart Association. Angina pectoris. http://www.americanheart.org/presenter.jhtml?identifier=4472. Accessed June 25, 2009.

  • Morrow DA, Gersh BJ. Chronic coronary artery disease. In: Braunwald E, Libby P, Bonow RO, Mann DL, Zipes DP, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 8th ed. Philadelphia, PA: Saunders Elsevier; 2008:1353,1354.

  • Data on file, Gilead Sciences, Inc.

  • Shoob HD, Croft JB, Labarthe DR. Impact of baby boomers on hospitalizations for coronary heart disease and stroke in the United States. Prev Med. 2007;44:447-451.

  • US Census Bureau. National population projections: (NP-T3) projections of the total resident population by 5-year age groups, and sex with special age categories: middles series, 1999 to 2100. Modified May 16, 2008. www.census.gov/population/www/projections/natsum-T3.html. Accessed November 19, 2008.

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